HEXAXIM

Hexaxim is a combination vaccine that protects against six serious diseases: diphtheria, tetanus, pertussis (whooping cough), hepatitis B, poliomyelitis (polio), and Haemophilus influenzae type b (Hib). This vaccine is commonly used in pediatric immunization programs.

How It Works

Hexaxim contains inactivated components of the bacteria and viruses that cause these diseases, which stimulate the immune system to develop immunity without causing the diseases themselves.

Administration

3 Dose Regimen:

• Primary Series: Three doses starting at 6 weeks of age, with a minimum interval of 1 month(4 weeks) between each dose.
• Booster: Administered at least 6 months after the last primary dose and preferably before 18 months of age.

2 Dose Regimen:

• Primary Series: Two doses with an interval of 2 months(8 weeks) between them.
• Booster: Given at least 6 months after the last primary dose, preferably between 11 and 13 months of age.
• Administered intramuscularly, usually in the upper thigh for infants (alternating thighs).
• If hepatitis B is given at birth as per the Expanded Programme on Immunization (EPI), the primary schedule is at 6, 10, and 14 weeks. Boosters follow the same schedule.
• Cannot be used for the second booster of DPT in children aged 4-7 years.

Side Effects

Common side effects may include:

• Pain or swelling at the injection site
• Fever
• Irritability
• Loss of appetite
• Fatigue

Severe reactions are rare.

Pregnancy and Lactation

• Pregnancy: Not applicable, as it is intended for infants and young children.
• Lactation: Not for adults. Safe for nursing mothers to administer to their infants.

Efficacy Studies

• Myth: The vaccine protection wanes off by 9 years of age. 
• Fact: Close to 100% seroprotection has been proven at 9 years of age.

Minimum Age Group

• Minimum Age: Approved for use in infants starting at 6 weeks old.
• Maximum Age: Recommended for children up to 2 years old.

Contraindications

• Allergic Reactions: Not for individuals with severe allergies to any component of the vaccine.
• Severe Illness: Vaccination should be postponed in cases of acute, severe febrile illness.

Hexaxim is an essential part of the routine immunization schedule for infants, providing comprehensive protection against six serious diseases. Consult healthcare providers for detailed vaccination schedules and personalized recommendations.