INDIRAB

Indirab Rabies Vaccine

Indirab is a vaccine used for the prevention of rabies, a deadly viral infection that affects the central nervous system. Rabies is primarily transmitted through the bite of an infected animal, and once symptoms appear, the disease is almost always fatal. Vaccination with Indirab is crucial for both pre-exposure prophylaxis in high-risk individuals and post-exposure treatment following potential exposure to the rabies virus.

How It Works

Indirab is an inactivated rabies vaccine, which means it contains a killed form of the rabies virus. This inactivated virus cannot cause the disease but is still capable of stimulating the immune system to produce antibodies. These antibodies provide immunity against the rabies virus, helping the body to fight off the infection if exposed in the future.

Administration

Pre-exposure Prophylaxis:

• Typically given in a series of three doses.
• Schedule: Day 0, Day 7, and Day 21 or 28.
• Recommended for individuals at high risk of rabies exposure, such as veterinarians, animal handlers, and travelers to areas where rabies is common.

Post-exposure Prophylaxis:

• Administered after potential exposure to the rabies virus.
• Schedule: Five doses on Days 0, 3, 7, 14, and 28, along with rabies immunoglobulin (RIG) on Day 0 for individuals who have not been previously vaccinated.

Administration Method: The vaccine is administered as an intramuscular injection, usually in the deltoid muscle of the upper arm for adults and older children, and in the anterolateral thigh for younger children.

Side Effects

Common side effects may include:

• Pain, redness, or swelling at the injection site
• Headache
• Nausea
• Muscle aches
• Fever

Severe allergic reactions are very rare.

Pregnancy and Lactation

• Pregnancy: Indirab can be administered during pregnancy if there is a risk of rabies exposure, as the benefits of vaccination outweigh the risks.
• Lactation: Safe for breastfeeding mothers. Consultation with a healthcare provider is recommended before administration.

Age Group

• Minimum Age: Indirab is approved for use in individuals of all ages, including infants, children, and adults.

Contraindications

• Allergic Reactions: Not recommended for individuals with a history of severe allergic reactions to any component of the vaccine.
• Severe Illness: Vaccination should be postponed in cases of acute, severe febrile illness, unless the exposure risk justifies immediate vaccination.

Nature of Antigen

• Nature of Antigen: Indirab contains inactivated (killed) rabies virus.

Vaccine Type

• Type: Indirab is an inactivated rabies vaccine.

Origin and Manufacturer

• Origin: Indirab is an Indian vaccine.
• Manufacturer: The vaccine is produced by Bharat Biotech, a leading biotechnology company in India.
• Introduction Year: Indirab was introduced in 2007.

Indirab is an essential vaccine for preventing rabies, offering both pre-exposure and post-exposure protection. Developed by Bharat Biotech, Indirab plays a critical role in public health by providing a reliable and effective means of rabies prevention. Whether for individuals at high risk of exposure or those who have been potentially exposed, Indirab is a vital component of rabies management. Always consult healthcare providers for personalized advice and vaccination schedules.