Enteroshield is a Typhoid Vi Conjugate vaccine designed to protect against typhoid fever, a serious illness caused by Salmonella Typhi bacteria. This vaccine is essential for individuals traveling to or living in areas where typhoid fever is endemic. Enteroshield contains Vi capsular polysaccharide of Salmonella Typhi conjugated to Tetanus Toxoid carrier protein, offering superior immune response compared to plain polysaccharide vaccines.
🏆 Global Recognition & Safety Standards
Enteroshield meets the highest international standards for vaccine quality and efficacy
⚡ Superior Immune Response - The Conjugate Advantage
- T-cell dependent immunity: Conjugation to Tetanus Toxoid creates a stronger, more robust immune response
- Longer-lasting protection: Enhanced immunological memory compared to non-conjugated vaccines
- Better effectiveness in young children: Works effectively even in infants as young as 6 months
- Superior to plain polysaccharide: Non-conjugated vaccines don't elicit T-cell response, making them less effective
How Enteroshield Works
Enteroshield contains inactivated components of the Salmonella Typhi bacteria, specifically the Vi capsular polysaccharide. When administered, it stimulates the immune system to develop protective antibodies against typhoid fever without causing the actual disease.
🧬 Advanced Conjugate Technology
- Vi Polysaccharide: The protective antigen from Salmonella Typhi capsule
- Tetanus Toxoid Carrier: Enhances immune recognition and response
- T-cell activation: Creates immunological memory for long-term protection
- Conjugation process: Chemical linking creates a more immunogenic vaccine
Important Protection Details
- Protection timeline: Immunity starts developing 2-3 weeks post-vaccination
- Specific coverage: Protects against Salmonella Typhi only
- Does NOT protect against: Salmonella Paratyphi or non-typhoidal Salmonella infections
- Protection level: High efficacy but not 100% - maintain hygiene practices even after vaccination
Enteroshield vs Plain Polysaccharide Vaccines
Superior Protection
- ✔ T-cell dependent immunity
- ✔ Long-lasting protection
- ✔ Effective from 6 months
- ✔ Booster response possible
- ✔ Stronger immune memory
- ✔ WHO & IAP prequalified
Plain Polysaccharide Vaccines
- ✗ No T-cell response
- ✗ Shorter duration of protection
- ✗ Only for ages 2+ years
- ✗ Limited booster response
- ✗ Weaker immune memory
- ✗ Older technology
Who Should Get Enteroshield?
✈️ Essential for Travelers & High-Risk Groups
- International travelers: Anyone visiting typhoid-endemic regions (South Asia, Africa, Latin America)
- Endemic area residents: People living in areas with high typhoid transmission
- Healthcare workers: Those with potential exposure to Salmonella Typhi
- Laboratory personnel: Workers handling typhoid cultures
- Close contacts: Household members of typhoid carriers
- Students: Those studying abroad in high-risk countries
Age Range - Comprehensive Coverage
- Minimum age: 6 months old
- Maximum age: 65 years
- Wide applicability: Suitable for infants, children, and adults
- Travel timeline: Get vaccinated at least 2-3 weeks before travel
💉 Administration & Dosage
Primary Dose
- Frequency: Single dose
- Volume: 0.5 mL
- Route: Intramuscular (IM) injection
Injection Site
- Infants/toddlers (until 2 years): Anterolateral thigh
- Children & adults (>2 years): Deltoid muscle (upper arm)
Booster Dose
- Timing: 3 years after primary vaccination
- For: High-risk individuals with continued exposure
- Not required: For low-risk individuals
Protection Timeline
- Onset: 2-3 weeks post-vaccination
- Duration: At least 3 years
- Travel planning: Vaccinate 2-3 weeks before departure
Side Effects
✓ Generally Well-Tolerated
Most people experience mild or no side effects. The vaccine has an excellent safety profile.
Common Side Effects (Mild & Temporary)
- Injection site reactions: Pain, redness, or swelling at the injection site
- Low-grade fever: Mild temperature elevation (usually resolves within 24-48 hours)
- Headache: Temporary and mild
- Fatigue: Mild tiredness or lethargy
- Muscle aches: General body discomfort
Note: These side effects typically resolve on their own within 1-2 days. Severe allergic reactions are extremely rare. Seek immediate medical attention if you experience difficulty breathing, severe swelling, or signs of anaphylaxis.
Pregnancy and Lactation
⚠️ Special Considerations for Women
- Pregnancy: Not recommended during pregnancy unless absolutely necessary. Discuss with your healthcare provider to weigh risks versus benefits if travel to typhoid-endemic area is unavoidable.
- Lactation: Not recommended during breastfeeding unless essential. Consult with your healthcare provider for personalized advice.
- Planning pregnancy: If possible, complete vaccination before conception
- Emergency situations: Healthcare provider may approve if travel risk outweighs vaccination concerns
Contraindications
When NOT to Get Enteroshield
- Severe allergic reactions: History of anaphylaxis or severe allergy to any vaccine component (Vi polysaccharide or Tetanus Toxoid)
- Acute severe illness: Postpone vaccination if you have a high fever or severe illness (mild illness is usually not a contraindication)
- Previous vaccine reaction: Severe reaction to a previous dose of Enteroshield
- Pregnancy: Generally not given (consult healthcare provider)
- Lactation: Generally not given (consult healthcare provider)
Always inform your healthcare provider about any allergies, medical conditions, or medications you are taking before vaccination.
Why Choose Enteroshield?
✓ The Smart Choice for Typhoid Protection
- WHO & IAP prequalified: Meets highest global standards for safety and efficacy
- Superior conjugate technology: T-cell dependent immunity for stronger, longer-lasting protection
- Single-dose convenience: Complete primary protection with just one shot
- Wide age range: Safe and effective from 6 months to 65 years
- Long-lasting protection: At least 3 years of immunity with option for booster
